Abstract
Hypertrophic Cardiomyopathy (HCM) is the most frequent hereditary cardiovascular disease and the leading cause of sudden cardiac death in young individuals. Advancements in CMR imaging have allowed for earlier identification and more accurate prognosis of HCM. Interventions aimed at slowing or stopping the disease’s natural course may be developed in the future. CMR has been validated as a technique with high sensitivity and specificity, very few contraindications, a low risk of side effects, and is overall a good tool to be employed in the management of HCM patients. The goal of this review is to evaluate the magnetic resonance features of HCM, starting with distinct phenotypic variants of the disease and progressing to differential diagnoses of athlete’s heart, hypertension, and infiltrative cardiomyopathies. HCM in children has its own section in this review, with possible risk factors that are distinct from those in adults; delayed enhancement in children may play a role in risk stratification in HCM. Finally, a number of teaching points for general cardiologists who recommend CMR for patients with HCM will be presented.
Highlights
Left ventricular outflow tract (LVOT) obstruction, mitral valve (SAM) or mitral regurgitation myocardial ischemia, fibrosis, and disarapparatus abnormalities such (MR), as systolic anterior motion myocardial (SAM) or mitral regurgitation ray aremyocardial the key characteristics of Hypertrophic Cardiomyopathy (HCM) that explain pathophysiology of the condition (MR), ischemia, myocardial fibrosis, and the disarray are the key characteristics of manifest clinically a variety[11]
These findings show that papillary muscle hypertrophy may be secondary to left ventricular (LV) pressure overload produced by LV obstruction rather than being caused by a primary genetic defect
CMR can distinguish between thrombi and based on tissue composition, as the latter exhibits a hyperintensity on T2-weighted imtumors based on tissue composition, as the latter exhibits a hyperintensity on T2-weighted ages, rendering it a useful tool for detecting hypertrophic cardiomyopathy complications images, rendering it a useful tool for detecting hypertrophic cardiomyopathy complications at the level of the left atrium
Summary
Hypertrophic cardiomyopathy (HCM) is a primary diffuse or segmental left ventricular hypertrophy in the absence of secondary causes capable of producing hypertrophy. It is the most common congenital cardiac disease, having a prevalence of 1 in 500 people and representing an important cause of sudden death in adolescents [1]. Left ventricular outflow tract (LVOT) obstruction, mitral valve (SAM) or mitral regurgitation myocardial ischemia, fibrosis, and disarapparatus abnormalities such (MR), as systolic anterior motion myocardial (SAM) or mitral regurgitation ray aremyocardial the key characteristics of HCM that explain pathophysiology of the condition (MR), ischemia, myocardial fibrosis, and the disarray are the key characteristics of [11]
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