Anatomic Location, Age, Gender and Staging of Osteosarcoma Patients Presenting to a Tertiary Care Centre

Abstract

Osteosarcoma is a high grade primary skeletal malignancy characterised by spindle cells of mesenchymal origin depositing immature osteoid matrix. With an annual incidence rate of 3.1 cases per million in the US, Osteosarcoma accounts for less than 1% of all newly diagnosed cancer in adults and 3-5% of those in children, but it is the most common malignancy in adolescents outside of leukemia and lymphoma. In India, the incidence varies from 4.7% to 11.6%, where this malignancy is associated with significant morbidity and mortality. Our study shows that Age distribution histogram shows a bimodal distribution. We observed that the most common site of osteosarcoma is around the knee joint in proximal tibia and distal femur. In our study we found that the tumour has higher prevalence in males than females. Most of the patients presented to us at Enneking stage 2b and AJCC stage 2a and 2b. Keywords: AJCC-American Joint Commission on Cancer