Abstract

Anaphylaxis is a serious, generalized, hypersensitivity reaction which can be life threatening and one of the most serious medical emergencies. Anaphylaxis in pregnancy although rare, is attributed to the use of various drugs in pregnancy mainly following an administration of antibiotics. This review article describes several aspects of anaphylaxis such as aetiology, pathophysiology and management. Immediate recognition and initiation of treatment are the keys for satisfactory outcome. A multidisciplinary care and provision are other keys for achieving this good outcome.

Highlights

  • Anaphylaxis is a serious, generalized, hypersensitivity reaction which can be life-threatening [1]

  • Anaphylaxis in pregnancy rare, is attributed to the use of various drugs in pregnancy mainly following an administration of antibiotics

  • Medications used in pregnancy such as ranitidine, snake antivenom are less commonly associated with anaphylaxis, so does bee sting [3]

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Summary

Introduction

Anaphylaxis is a serious, generalized, hypersensitivity reaction which can be life-threatening [1]. It is one of the most serious medical emergencies, where rapid diagnosis and prompt and appropriate treatment save lives. A prospective population-based study on anaphylaxis in pregnancy by Mc Call et al [2], has shown that anaphylaxis is a rare but potentially serious event in terms of maternal and fetal outcomes It is frequently the result of a reaction to antibiotic administration mostly because of the prophylactic use of antibiotics at the time of a cesarean section [CS] [2].

Aetiology
Pathophysiology
The Patterns of Anaphylaxis Reaction
Diagnosis and Differential Diagnosis
Severity of Anaphylaxis
Management
Findings
Conclusion
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