Abstract
In their classic studies of anaphylaxis, Portier and Richet described the rapid death of several dogs that they were attempting to immunize against the toxic sting of the sea anemone. 36,53 Because this reaction represented the opposite of their intended prophylaxis, they coined the term anaphylaxis, or without or against protection. From these studies, they concluded that anaphylaxis required a latent period for sensitization and re-exposure to the sensitizing material. Shortly thereafter, Schlossman reported a patient who developed acute shock after the ingestion of cow's milk. 2 The first series of modern-day descriptions of food anaphylaxis in humans was published in 1969 by Goldbert et al. 18 They described 10 cases of anaphylaxis following the ingestion of various foods, including different legumes, fish, and milk.
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