Abstract
A 68-year-old female patient self-medicated with 1 tablet of compound paracetamol and amantadine hydrochloride (each tablet contained acetaminophen 250 mg, amantadine hydrochloride 100 mg, calculus bovis factitious 10 mg, caffeine 15 mg, and chlorpheniramine maleate 2 mg) because of nasal discharge and cough on the second day of trabeculectomy with covering of amniotic membrane in her right eye. About 30 minutes after administration, she developed dizziness, nausea, vomiting, urinary incontinence, itching on her arms and calves, and pale. Her blood pressure was 80/44 mmHg and heart rate was 90 beats/min. Anti-allergic treatments, blood volume expansion, and oxygen mask were given. Thirty minutes later, her blood pressure increased to 90/62 mmHg. The patient's symptoms gradually alleviated 2 hours later and the blood pressure increased to 106/69 mmHg 6 hours later. Key words: Compound paracetamol and amantadine hydrochloride; Anaphylaxis
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