Abstract
BackgroundAlthough a few case reports about hypertensive anaphylaxis (HA) are available in the present literature, there is no study about the prevalence of HA. In this study, we review our cases with anaphylaxis presenting with hypertension and ascertain its prevalence. The documents of the patients who had anaphylactic reactions after the procedures performed for the diagnosis and treatment of allergic diseases in GATA Haydarpasa Clinic of Allergy and Immunology between January 2010 and December 2014 were retrospectively reviewed. Within the study period, 324 patients had undergone 4332 procedures in which 62 of them had developed anaphylaxis.ResultsDuring the procedures, the rate of anaphylaxis was found to be 1.43 %. The rate of HA among the anaphylaxis patients was 12.9 % (8 of 62 patients). During treatments, 2 patients received adrenaline injections without any adverse reaction.ConclusionsHA may be seen at a considerable rate during an anaphylactic reaction. Anaphylaxis and hypertension can be recovered by adrenaline injection when required. According to the best of our knowledge, this study is the first original study about the prevalence of HA in English-language medical literature.
Highlights
A few case reports about hypertensive anaphylaxis (HA) are available in the present literature, there is no study about the prevalence of HA
The documents of the patients who had anaphylactic reactions after the procedures performed for the diagnosis and treatment of allergic diseases in Gulhane Military Medical Academy (GATA) Haydarpasa Clinic of Allergy and Immunology between January 2010 and December 2014 were retrospectively reviewed
Patients who had been previously diagnosed with hypertension, treated for hypertension or measured hypertensive as basal blood pressure were excluded from the study
Summary
A few case reports about hypertensive anaphylaxis (HA) are available in the present literature, there is no study about the prevalence of HA. We review our cases with anaphylaxis presenting with hypertension and ascertain its prevalence. The documents of the patients who had anaphylactic reactions after the procedures performed for the diagnosis and treatment of allergic diseases in GATA Haydarpasa Clinic of Allergy and Immunology between January 2010 and December 2014 were retrospectively reviewed. Diagnosis of anaphylaxis is usually based on the history of allergen exposure and physical findings (Sampson et al 2006; Simons 2010). Other than the upper airway obstruction, cardiovascular collapse is the second most life-threatening anaphylactic reaction which requires an urgent treatment. Hypotension is the most common cardiovascular system finding and considered to be a criterion for diagnosis Reduced blood pressure after exposure is known to be the leading indicator of anaphylactic reaction (Muraro et al 2014).
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