Abstract

The content of human sweat is studied by high-resolution NMR, and the majority of organic components most often found in sweat of conditionally healthy people are identified. Original and simple tools are designed for sweat sampling from different areas of human body. The minimal surface area needed for sampling is in the range of 50–100 cm2. On all the surface parts of the human body examined in this work, the main constituents forming a sweat metabolic profile are lactate, glycerol, pyruvate, and serine. The only exception is the sole of the foot (planta pedis), where trace amounts of glycerol are found. An attempt is made to explain the presence of specified metabolites and their possible origin.

Highlights

  • Modern high-resolution NMR techniques provide an opportunity to study a wide spectrum of biological objects, including various biological fluids, which are often complex mixtures of organic and inorganic components

  • The studying of biological fluids by NMR is a promising direction of modern metabolomics, which analyze metabolic profiles to understand the processes occurring in living organisms

  • The analysis of content changes of some components in biological fluids is widely used in medicine

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Summary

Introduction

Modern high-resolution NMR techniques provide an opportunity to study a wide spectrum of biological objects, including various biological fluids, which are often complex mixtures of organic and inorganic components. We report the high-resolution NMR analysis of the composition of sweat samples systematically obtained from different parts of the body using a set of specially constructed tools.

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