Abstract
Novel chemicals with persistent organic pollutant characteristics have been focused increasing attention by governmental agencies and scientific communities. Researches on analytical methodologies are critical on identification of novel chemical pollutants, which is challenged by the facts that: (1) no specific chemicals are used as target analytes; (2) pollutant residue concentrations are usually in trace levels; (3) severe matrix effects exist in complex environmental compartments. Consequently, multiple advanced techniques are urgently needed to establish an efficient system for chemical recognition and structure elucidation. This review summarises the recent progress in key analytical strategies on sample pretreatment, tracing protocols, and multiple chemical information integration. Current knowledge gaps and future trends are also discussed.
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