Abstract

Introduction: Guduchi is a highly potential drug which is mentioned in Ayurveda classics. The clinical utility of this drug is widely known. The Tinospora species are wrapped under the broad spectrum Guduchiin the Ayurveda classics. Tinospora is one of the important genera of the family, consisting of about 15 species. Some medicinally important species includes T. cordifolia, T. malabarica, T. tomentosa, T. crispa, T. uliginosa, T. crispaetc. In the current article the drug Tinospora crispa is considered in detail.Tinospora crispa is used irrationally by the society owing to its various therapeutic benefits. Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae), found in the rainforests or mixed deciduous forests in Asia and Africa, is used in traditional medicines to treat numerous health conditions.
 Materials & Methods: A detailed review of the drug has been carried out through the available literature. After considering the review the analytical profiling of the drug has been done.The phytochemical analyses review of T. crispa revealed the presence of alkaloids, flavonoids, and flavone glycosides, triterpenes, diterpenes and diterpene glycosides, cis clerodane-type furanoditerpenoids, lactones, sterols, lignans, and nucleosides. The literary review showed that the crude extracts and isolated compounds of T. crispa possessed a broad range of pharmacological activities such as anti-inflammatory, antioxidant, immunomodulatory, cytotoxic, antimalarial, cardioprotective, and anti-diabetic activities.So, in the current research study a sincere attempt has been made to study regarding the drug Tinospora crispa through its analytical profile.
 Results: Through this research article able to make out the available literature and the analytical profile of the drug Tinospora crispa.
 Discussion: The current analytical profile reveals the presence of alkaloids, tannins, flavonoids, saponins etc which directly connects to the various activities like Anti-pyretic, Anti- inflammatory, Antioxidant etc of the drug Tinospora crispa.
 Conclusion: The current research study points towards the review of the drug and the analytical profile which is beneficial to carry out the next phase of research studies in connection with this drug Tinospora crispa.

Highlights

  • Guduchi is a highly potential drug which is mentioned in Ayurveda classics

  • Quantitative indication of acidic nature of the drug Indicates the loss of amount of water & other volatile impurities present in the sample It indicates the purity of the drug As per API, for Tinospora cordifolia it should not be

  • The analytical studies conducted on this drug prove the features of Tinospora crispa.We tried to document the existing phytochemistry, pharmacological properties, and application researches on T. crispa

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Summary

Introduction

Guduchi is a highly potential drug which is mentioned in Ayurveda classics. Guduchi has been acclaimed as a highly potential drug in Ayurveda, for preservation of health, prevention of disease and curative measures. It is attributed with a wide range of pharmacological activities. Vanaras (monkey soldiers) who had died were given a new life by Lord Indra through sprinkling of nectar. During this act when the drops of nectar (Amruta) fell on the ground, Guduchi plant originated

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