Abstract
The present research work discusses the development and validation of a UV spectrophotometric method for ornidazole. Simple, accurate and cost efficient spectrophotometric method has been developed for the estimation of ornidazole in pure drug form. The optimum conditions for the analysis of the drug were established. The maximum wavelength (λ max) was found to be 430 nm. Beers law was obeyed in the concentration range of 1μg/mL. Calibration curves shows a linear relationship between the absorbance and concentration. Validation was performed according to ICH guidelines for Linearity, accuracy, precision, LOD (limit of detection) and LOQ (limit of quantification). The sample solution was stable up to 36 hours. The proposed method may be suitable for the analysis of ornidazole in drug formulation for quality control purposes.
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