Abstract
In the current work, a simple and extraction free UV spectrophotometric technique was developed and validated for the estimation of ETR as per ICH guidelines. ETR approach has been created using the pure drug. The drug demonstrates effective absorption in the Concentration Range of 1-5μg/ml at 311nm and linearity. The technique relay on the response of the drug with MeOH to get the colourless solution. Absorbance was measured at its absorption maximum (λ max) 311nm. Beer's regulation has been obeyed in the concentration vary of 1-5μg/ml. The calibration graph was determined to be linear, and the Coefficient of correlation (r2) was found to be 0.9956%. The recommended method's analytical activity parameters LOD and LOQ were calculated respectively as 1.91 and 2.67μg/mL. Recovery for ETR was discovered to be 100.71 percent. To optimize the response situation, all variables had been examined.
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