Abstract
In this paper, an approximate analytical method to solve the non-linear differential equations in an immobilized enzyme film is presented. Analytical expressions for concentrations of substrate and product have been derived for all values of dimensionless parameter. Dimensionless numbers that can be used to study the effects of enzyme loading, enzymatic gel thickness, and oxidation/ reduction kinetics at the electrode in biosensor/biofuel cell performance were identified. Using the dimensionless numbers identified in this paper, and the plots representing the effects of these dimensionless numbers on concentrations and current in biosensor/biofuel cell are discussed. Analytical results are compared with simulation results and satisfactory agreement is noted.
Highlights
Biosensors and biofuel cells are commonly used for industrial, environmental and medical applications
There are no clear guidelines for the design of electrochemical biosensors or biofuel cells employing immobilized enzymes that will produce a targeted linear range, limit of detection and sensitivity
The result of the Equations (2)-(3) in immobilized enzyme system is relevant because its solution describes important applications such as biosensors, bioreactors, and biofuel cells, among others
Summary
Biosensors and biofuel cells are commonly used for industrial, environmental and medical applications. There are no clear guidelines for the design of electrochemical biosensors or biofuel cells employing immobilized enzymes that will produce a targeted linear range, limit of detection and sensitivity. Such guidelines can be provided using analytical simulation tools that assess sensor feasibility prior to extensive development. Electrochemical biosensors and biofuel cell especially desirable for use in field applications because of their compact design, ease of manufacture, real time response, sensitivity and selectivity [3]-[6] They are used in many applications ranging from glucose detection to detection of neurotoxic agents [1] [6] [7]. The result of the Equations (2)-(3) in immobilized enzyme system is relevant because its solution describes important applications such as biosensors, bioreactors, and biofuel cells, among others
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
