Abstract

Some biological bonds exhibit a so-called catch regime, where the bond strengthens with increasing load. We build upon recent advances in slip-bond kinetics to develop an analytically tractable, microscopic catch-slip bond model. To facilitate the analysis of force-spectroscopy data, we calculate the bond's mean lifetime and the rupture-force distribution for static loading and linear force ramps. Our results are applicable for arbitrary forces and loading rates, covering the whole range of conditions found in experiments and all-atom simulations. A generalization to account for force transducers of finite stiffness is also provided.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.