Abstract

Objectives To study the expression of PBRM1 and P53 in renal cell carcinoma (RCC) and its clinical significance.Methods The protein of PBRM1 and P53 was examined in 66 cases of RCC immunohistochemistry.Results The positive rate of expression of PBRM1 and P53 were 62.1％ and 39.4％ ( P ＞ 0.05 ).Conclusions The expression level of PBRM1 increased markedly with the clinical stage or clinical grade of RCC and it could be related to the biological behavior of neoplasms.But P53 plays an unimportant role in RCC. Key words: Kidney Neoplasms; Protein P53; Immunohistochemistry

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