Abstract
Aim: To summarize and analyze the clinical and endoscopic parameters in patients with reflux esophagitis(RE). Methods：1247 patients with RE were diagnosed in our hospital endoscopy center from September 2010 to August 2012. The general information of the patients and the relationship between endoscopic classification and concomitant diseases were analyzed. Results: According to the endoscopic findings, 1247 subjects (4.70%) were found to have RE：932 (74.74%) males and 315 (25.26%) females, and the male to female ratio was 2.96:1. The peak age of prevalence was 50 to 59 (27.35%) which is followed by 40 to 49 (23.10%). In this study, most of the patients had a mild degree of esophagitis representing LA-A in 60.63% and LA-B in 34.24%. The antrum hyperemia was found in 291 patients with esophagitis (23.34%), followed by antrum erosion (20.13%) and hatal hernia (15.88%). There is no statistically significant relevance between Helicobacter pylori infection and RE (P > 0.05), but Barrett’s esophagus, duodenal ulcer, gastroesophageal tumors, a history of gastroesophageal surgery and antrum hyperemia were found to be associated with RE (P . Conclusion: The prevalence rate of endoscopic RE in our study was 4.70%, and most patients had a mild grade esophagitis. Male, advanced age, Barrett’s esophagus, duodenal ulcer, gastroesophageal tumors and a history of gastroesophageal surgery are the risk factors of esophagitis. Antrum hyperemia may reduce the severity of RE.
Highlights
Gastroesophageal reflux disease (GERD) is defined as troublesome symptoms and/or complications due to abnormal reflux of gastrointestinal contents into the esophagus [1,2,3,4,5]
The esophagitis is more prevalent among male than female (74.74% in male and 25.26% in female), with the male: female ratio being 2.96:1
One mucosal break that is continuous between the tops of two or more mucosal folds but which involves less than 75% of the circumference
Summary
Gastroesophageal reflux disease (GERD) is defined as troublesome symptoms and/or complications due to abnormal reflux of gastrointestinal contents into the esophagus [1,2,3,4,5]. It is often combined with esophageal mucosal injury which is called reflux esophagitis (RE). GERD was considered as a very uncommon disease in Asia, but the disease seemed to be increasing [2,3]. RE has been classified as a typical manifestation of GERD, which has a seriously impact on the quality of the patient’s life by suffering boring symptoms and diverse complications. To further enhance the awareness of the disease and to summarize the features of epidemiology and endoscopy of RE, we conducted a retrospective analysis of 1247 patients with RE, which was diagnosed endoscopically in our hospital
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