Analysis on the application of biosensor in forensic detection

Abstract

This essay simple analysis the advantages and disadvantages of three various biosensor technologies: Gas Chromatography-Mass Spectrometry (GC-MS), Liquid Chromatography-Mass Spectrometry (LC-MS), and Immunoassays. The rapid advancements in biosensing technology have revolutionized for the last few years, these biosensors have revolutionized forensic science by enabling analysis of various compounds, aiding in crime scene investigations, drug testing, and toxicological analysis. Firstly, GC-MS offers outstanding sensitivity and specificity. It allows for the detection of complex mixtures, providing valuable information for identifying substances such as drugs and explosives. However, GC-MS requires time-consuming sample preparation methods, limited applicability to volatile analytes. As well as advanced technical expertise, which can pose challenges for forensic laboratories. Second, LC-MS has shown advantages in analyzing a wide range of non-volatile and polar compounds, making it invaluable in forensic toxicology. LC-MS provides excellent sensitivity and selectivity. Promoting the detection and quantification of pharmaceuticals, illicit drugs, and their metabolites. Lastly, immunoassays provide a simpler and faster substitute for forensic analysis. These assays rely on specific antigen-antibody interactions and are capable of detecting a variety of analytes, such as drugs, hormones and toxins. They offer fast turnaround times, cost effectiveness, and compatibility with point-of-care diagnostics.