Analysis on immune status of the new found HIV infected persons in Hebei Province in 2009

Abstract

Objective To analyze immune status of 300 newly reported HIV cases in Hebei Province in 2009.Methods Flow cytometry was used to detect CD4 + T lymphocytes of the infected persons ;data was analyzed by SPSS 15.0 software.Results The average of CD4 + T lymphocytes in male and female patients were 366.36 ± 14.16 and 303.74 ±26.06 separately.The male' s was higher than the female' s (P＜0.05),but was still far below that of healthy population (860.27 ± 255.15).Among the groups elder than 9 years old,CD4+T lymphocytes in age group 20-29 was statistically highest(425.59 ± 21.48,P ＜0.05 ).CD4 + T lymphocytes in unmarried group was higher than married group with significant statistical difference(P ＜ 0.05 ).As to the routes of transmission,isosexual mode was significantly different with heterosexual,injecting drug,blood transmission,and other unknown modes ( P ＜ 0.05 ) ; injecting drug route was significantly different ( P ＜ 0.05 ) with isosexual,heterosexual,blood transmission and other unknown routes.Difference between groups by occupation and education was not statistically significant ( P ＞ 0.05 ).Conclusions In the newly reported HIV cases of Hebei province in 2009,CD4 + T lymphocytes level is statistically different with gender,age,marital status and route of transmission.Main factors influencing immune status of newly reported cases are age,transmission mode and detection testing timeliness. Key words: Human immunodeficiency virus; CD4 + T lymphocytes; Influencing factors