Analysis on human brucellosis from national reports in China, 2006-2016

Abstract

Objective To characterize the features of human brucellosis from national reports of occupational diseases and infectious diseases in China during 2006-2016, and explore the correlations between human brucellosis with the livestock and their products. Methods From January to October 2018, the data of human brucellosis were extracted from China's annual national reports of occupational diseases and infectious diseases from government circulars during 2006-2016. The data on the number of livestock and the output of livestock products were obtained from China Statistical Yearbook, China Animal Industry Yearbook and China Animal Industry and Veterinary Yearbook. The standards of Diagnosis of occupational infectious disease (GBZ 227-2017) and Diagnostic criteria for brucellosis (WS 269-2007) were compared. The statistics were analyzed using Excel 13.0 and SPSS software 22.0. The linear regression and multiple regression were used to explore the relationships between human brucellosis with the number of livestock and the output of livestock products. Results The diagnosis of human brucellosis in national reports of occupational diseases was based on GBZ 227-2017, which referred to WS 269-2007. There is an increasing trend from 2006 to 2009, and then declined to 2011, but rebounded from 2012 onwards in human brucellosis in national reports of occupational diseases. The general trend showed an increase during the 2006-2014 period, and then a decrease onwards in human brucellosis in national reports of infectious diseases. The Spearman correlation from SPSS showed the rs value of 0.936 (P<0.001) between human brucellosis cases in national reports of occupational diseases and infectious diseases in China from 2006 to 2016. Human brucellosis had a seasonal and periodic trend, and the cases revealed an epidemic period from April to August, with a peak in June. Human brucellosis cases were positively correlated with the number of cattle and buffaloes, hogs, sheep and goats (P<0.05) , and the output of pork, beef and mutton (P<0.05) . And human brucellosis cases in national reports of infectious diseases were positively associated with the output of sheep wool (β=0.814) , goat wool (β=0.603) , and cashmere (β=0.562) . Conclusion Human brucellosis both in national reports of occupational diseases and infectious diseases remain severe in China. There are relationships between human brucellosis with the number of livestock and the output of livestock products. Key words: Human brucellosis; Occupational diseases; Communicable diseases; Diagnostic criteria; Regression analysis