Abstract
Objective To evaluate the curative effect of different radiotherapy methods in no-metastasis and lesion length ≤ 5.0 cm esophageal squamous cell carcinoma (ESCC). Mothods A total of 158 eligible patients were retrospectively analyzed. The treatment out comes prognosis factors, and toxicity were evaluated. Results There were no significantly differences in curative effect for ENI and IFI group(χ2=2.17, P>0.05). Compared with IFI group, the OS and TSS were significantly higher than in ENI group (χ2=11.21, 8.57, P<0.05), and the LR ratio and DM ratio were significantly lower than that of the IFI patients (χ2=4.99, 7.48, P<0.05). Multivariate analysis showed that ECOG grade and short-term effect (χ2=15.05, 10.32, P<0.05) were the independent prognostic factor for IFI, while the maximum diameter of CT(χ2=8.32, P<0.05) was the independent prognostic factor for ENI. There were no significant differences in acute radiation esophagitis and pneumonitis between ENI and IFI groups. Conclusions Radiotherapy in combination with chemotherapy has a good curative effect in no-metastasis and lesion length ≤ 5.0 cm ESCC patients. More survival benefit might be achieved by ENI than IFI. Key words: Esophageal neoplasms; Radiotherapy mode; Efficacy
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