Analysis on colonoscopic results of screening 1 990 community people with high-risk of colorectal cancer

Abstract

Objective To investigate the prevalence of colorectal cancer in community people in Shanghai, and clarify the necessity of colorectal cancer screening in community residents. Methods From April 2013 to September 2014, colonoscopy examination was carried out in people who participated in colorectal cancer screening in Shanghai with positive result of fecal occult blood test or with high-risk in colorectal cancer evaluated with the risk factors questionnaire. A total of 1 990 individuals were recruited. The colonoscopic results of them were retrospectively analyzed. Chi-square test was performed for statistical analysis. Results The 1 990 individuals received colonoscopy examination aged from 50 to 92. Among the 1 990 individuals with colonoscopy examination, colorectal polyps, colorectal cancer and carcinoid were found in 1 027 cases, and the total detection rate was 51.6%. The detection rate of colorectal polyps was 48.7% (969/1 990), and the maximum diameter of polyps was 3.5 cm. The detection rate of colorectal polyps of the male was 59.3% (532/897), which was higher than that of the female (40.0%, 437/1 093), and the difference was statistically significant (χ2=73.7, P<0.01). The detection rate of colorectal polyps in group 50 to 60 (not include 60) years old, 60 to 70 (not include 70) years old, 70 to 80 (not include 80) years old and ≥80 years old was 37.5% (139/371), 48.7% (524/1 075), 55.9% (248/444) and 58.0% (58/100), respectively. The difference was statistically significant (χ2=31.3, P<0.01). The detection rate of colorectal cancer was 2.7%(54/1 990). The detection rate of male rectal cancer was 3.8% (34/897), which was significantly higher than that of female (1.8%, 20/1 093), and the difference was statistically significant (χ2=7.2, P<0.05). The detection rate of colorectal cancer in group 50 to 60 (not include 60) years old, 60 to 70 (not include 70) years old, 70 to 80 (not include 80) years old and ≥80 years old was 1.6% (6/371), 1.9% (20/1 075), 4.3% (19/444) and 9.0% (9/100), respectively. The difference was statistically significant (χ2=23.7, P<0.01). The detection rate of rectal carcinoid was 0.2% (4/1 990). Conclusions The prevalence of colorectal polyps and cancer is high in screening community people with high-risk of colorectal cancer. Colorectal cancer screening in community people ≥50 years old with sequential screening method is important. Key words: Colorectal neoplasms; Colorectal polyps; Colonoscopy; Screening