Abstract
Objective: The objective of the present study is to explore the vipaka of an extra-pharmacopoeia drug Bridelia stipularis (L.) Blume belongs to the Euphorbiaceae family.
 Methods: 12 Wistar strain albino rats were selected and divided into 2 groups; Group A-Control, Group B-Test group. Each rat was kept in separate metabolic cages provided with a constant amount of water and food per day. Assessment of vipaka was done based on the consumption of food, consumption of water, the quantity of faecal matter, urine output, and quantity of water content of expelled faecal matter per day. Assessment of Vipaka was done on the basis of consumption of food; consumption of water; the quantity of faecal matter, urine output and quantity water content of expelled faecal matter per day. Assessment of Vipaka was done on the basis of consumption of food; consumption of water; the quantity of faecal matter, urine output and quantity water content of expelled faecal matter per day.
 Results: Absolute values of Group B or test group exhibited significant increase in water consumption (p<0.01), wet faecal matter (p<0.05), dry faecal matter (p<0.001), and food conversion ratio (p<0.05), and non-significant increase in food consumption, urine output, faecal water, and body weight.
 Conclusion: Based on the preliminary analysis it may be concluded that the drug Bridelia stipularis (L.) Blume possess Madhura vipaka (Sweet metabolic transformation).
Highlights
Ayurvedic science has got an immense database of herbal drugs
The decoction of wood is used in the treatment of Malaria disease [3]
Bridelia stipularis (L.) Blume was collected from Chelari, Malappuram district, Kerala and authenticated from CMPR (Centre for Medicinal Plant Research), Aryavaidyasala, Kottakkal, Kerala, India
Summary
Ayurvedic science has got an immense database of herbal drugs. It is becoming increasingly popular worldwide with many chronic conditions responding to it well. Bridelia stipularis (L.) Blume is one of the extra-pharmacopoeial drugs having wide uses It is a large woody evergreen climber or straggling shrub belonging to the family Euphorbiaceae and is distributed in South-east Asia like the central and eastern parts of Bangladesh, India, and Myanmar (Kritikar K R et al.,1975). Different parts of this plant are applicable for various treatments. The decoction of wood is used in the treatment of Malaria disease [3]
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