Abstract
Extremely low plasma ANP levels in DKA associated with severe volume depletion suggest a negative feedback regulation of the hormone. In DKA the plasma volume and sodium regulating hormonal systems are markedly altered by the volume depletion. Plasma concentrations of vasoconstrictor and sodium and water retaining hormones like AVP, renin, aldosterone and noradrenaline are increased, whereas that of ANP, with potent vasodilator and natriuretic properties, is suppressed. Following volume repletion, most of the alterations are reversible.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
