Abstract
The gum resin of Boswellia serrata, also known as Indian frankincense, is a commonly used traditional medicine with many desired pharmacological, especially anti-inflammatory, effects. They are due to specific acidic triterpenes in the plant, boswellic acids (BAs) [1]. Even though many techniques have been evaluated for their analysis, the use of Supercritical Fluid Chromatography has never been considered before. In this study, the baseline separation of six boswellic acids, all derivatives of α- and β-BA, in less than 6 min by SFC is described, using a Viridis HSS C18 SB column and a mobile phase comprising carbon dioxide and a mixture of methanol, acetonitrile and ammonium hydroxide. In respect to speed this surpasses all other currently known analytical approaches. The method was successfully validated following ICH guidelines (e. g., R2≥0.999, LOD≤5.5 mg/mL)
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
