Abstract

Recent reports from phase III trials (PARADIGM, DECIDE) did not demonstrate a survival benefit with the addition of IC to CRT for head and neck squamous cell carcinoma, however these trials did not specifically address patients with OPSCC. We analyzed our experience treating OPSCC to determine if this subgroup of patients benefits from the addition of IC with docetaxel, cisplatin, 5-fluorouracil (TPF) to platinum based CRT, which is the current standard of care for locoregionally advanced OPSCC.

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