Abstract
Objective: To verify the influence of the osteopeny induced by the bone repairing of the receptor site/autogenous bone graft block interface either associated with or without PTFE-e membrane through the analysis of the trabecular bone volume. Material & Methods: 48 Wistar rats weighing approximately 300 g were submitted to parietal bone graft which was fixed to the lateral wall of the left mandibular ramus. The animals were randomly divided into four groups: Group 1: simulated ovariotomy (SHAM) and autogenous bone graft; Group 2: SHAM and autogenous bone graft through PTFE-e membrane recovering; Group 3: ovariotomy (OVZ) and autogenous bone graft; Group 4: OVZ and autogenous bone graft and PTFE-e membrane recovering. The animals of each group were killed at the following periods: 21, 45 and 60 days, comprising 4 animals per group. The pieces were decalcified and included; the cuts were stained with HE and submitted to histological and histomorphometric analysis through light microscopy. Results: ANOVA test showed that the variables accounting for both the condition (OVZ and SHAM) and the period (21,45 and 60 days) were statistically significant; the Tukey test (5%) showed that the period of 21 days was statistically different from 45 and 60 days; however, they were not statistically different between each other. The descriptive histological analysis showed grafting integration in all animals. Conclusion: the process of graft integration with the receptor site was negatively affected by the induced osteopeny presence and presence or absence of PTFE-e membrane did not interfered in the integration process.
Highlights
The osseointegrated implants are excellent alternative for rehabilitation, either functionally or aesthetically, of single or multiple prosthetic spaces
The aim of this study was to assess the influence of the induced osteopeny on the repairing process of autogenous bone grafts either associated with or without PTFE-e membrane through the analysis of the trabecular volume in Wistar rats submitted to ovariotomy (OVZ) and simulated ovariotomy (SHAM)
The animals were randomly divided into two experimental groups which were subdivided into subgroups: a)test group: 24 ovariectomized rats (OVZ) OVZ – E: 12 animals submitted to bone grafting only; OVZ – ME: 12 animals submitted to bone grafting associated with the recovering by expanded polytetrafluoroethylene (PTFE-e) membrane b) control group controle: 24 rats submitted to simulated ovariotomy (SHAM) SHAM – E: 12 animals submitted to bone grafting only; SHAM – ME: 12 animals submitted to bone grafting associated with the recovering by PTFE-e membrane
Summary
Maria Aparecida Neves JARDINI1, Andrea Carvalho DE MARCO1, Antonio Braulino de Melo FILHO2, Rodrigo Dias NASCIMENTO1, Warley David KERBAUY1, Mauro Pedrine SANTAMARIA1 1 - Institute of Science and Technology - UNESP – Univ Estadual Paulista, School of Dentistry - Department of Diagnosis and Surgery – São José dos Campos – SP – Brazil. 2 - Institute of Science and Technology - UNESP – Univ Estadual Paulista - School of Dentistry - Department of Social Science and Pediatric Dentistry – São José dos Campos – SP – Brazil.
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