Abstract
In the genome of antibiotic-sensitive Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin. Analysis if its structure revealed that it does not contain genes of resistance to such antibiotics as streptomycin, sulfamethoxasole, trimethoprim, chloramphenicol, and kanamycin, being, probably, one of the predecessors of antibiotic-resistant SXT constins which spread out within the genomes of epidemic Vibrio cholerae O139 strains in 1992.
Highlights
In the genome of antibiotic-sensitive Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin
В отличие от эпидемических штаммов О139 серогруппы и R931 элемента SXT констин штамма Р-8845 не содержит генов устойчивости к антибиотикам Su, Tm, Cm, Sm, Kn, обычно входящих в состав этого семейства сложных конъюгативных транспозонов
Summary
Analysis of the SXT Constin of Antibiotic-Sensitive Vibrio cholerae Strain of Non-O1/ Non-O139 Serogroup In the genome of antibiotic-sensitive Vibrio cholerae strain belonging to O50 serogroup, isolated in the territory of the Russian Federation in 1974, detected is the SXT conjugative trasposone – SXT constin.
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