Abstract
Objective: The use of human induced pluripotent stem cells (hiPSCs) and recent advances in cell engineering have opened new prospects for cell-based regeneration therapy. However, there are concerns that must be addressed prior to their broad clinical applications such as treatment for Parkinson's disease, and a major concern is tumorigenicity. We here generated knock-in hiPSCs to analyze the feasibility of the herpes simplex virus thymidine kinase (HSV-TK) suicide gene system as a safeguard against tumorigenicity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
