ANALYSIS OF THE RADIOGRAPHIC ASPECTS OF LYMPHOMAS AND LEUKEMIAS AFFECTING GNATHIC BONES

Abstract

Lymphomas and leukemias are malignant neoplasms that uncommonly affect the jaws and their radiographic manifestations may contribute to the diagnosis. Objective: To investigate the radiographic features of lymphomas and leukemias in the jaw bones. Study Design: systematic review in the electronic databases Pubmed, Web of Science, and Scopus using the key words "lymphoma, leukemia, mandible, maxilla, jaw, gnathic bones", between 2008 and 202. Inclusion criteria: Periapical, panoramic, or computed tomography (CT) images for individual cases and diagnosis of lymphoma/leukemia confirmed by immunohistochemistry. Three authors described the images and evaluated the quality of the radiographic exams. Results: From 1079 reports screened, 130 cases were selected containing 88 tomographic, 78 panoramic, and 26 periapical exams, most of them classified as excellent (54%). Diffuse large B-cell lymphomas NOS (DLBCL), Burkitt lymphoma, leukemic infiltration, and plasmablastic lymphoma were the more common subtypes. Involved teeth presented mobility in 36% and a provisional diagnosis of inflammatory/infectious tooth disease was considered 48% of the cases. Most cases were radiolucent and conventional CT exams were available for 76% of the cases, with hypodense aspect, ill-defined borders, and periosteal reactions were uncommon. Conclusion: Lymphomas with gnathic bone destruction are usually of high-grade subtypes and rarely present periosteal reaction. Lymphomas and leukemias are malignant neoplasms that uncommonly affect the jaws and their radiographic manifestations may contribute to the diagnosis. Objective: To investigate the radiographic features of lymphomas and leukemias in the jaw bones. Study Design: systematic review in the electronic databases Pubmed, Web of Science, and Scopus using the key words "lymphoma, leukemia, mandible, maxilla, jaw, gnathic bones", between 2008 and 202. Inclusion criteria: Periapical, panoramic, or computed tomography (CT) images for individual cases and diagnosis of lymphoma/leukemia confirmed by immunohistochemistry. Three authors described the images and evaluated the quality of the radiographic exams. Results: From 1079 reports screened, 130 cases were selected containing 88 tomographic, 78 panoramic, and 26 periapical exams, most of them classified as excellent (54%). Diffuse large B-cell lymphomas NOS (DLBCL), Burkitt lymphoma, leukemic infiltration, and plasmablastic lymphoma were the more common subtypes. Involved teeth presented mobility in 36% and a provisional diagnosis of inflammatory/infectious tooth disease was considered 48% of the cases. Most cases were radiolucent and conventional CT exams were available for 76% of the cases, with hypodense aspect, ill-defined borders, and periosteal reactions were uncommon. Conclusion: Lymphomas with gnathic bone destruction are usually of high-grade subtypes and rarely present periosteal reaction.