Analysis of the predictive value of preventive isolation criteria in the intensive care unit

Abstract

To assess the diagnostic accuracy of the criteria used to detect patients carrying multiresistant microorganisms (MRMs). A prospective observational study was carried out from May 2014 to May 2015. Polyvalent Intensive Care Unit. A cohort of consecutively admitted patients meeting the following criteria for preventive isolation according to the "Zero Resistance" project: hospital length of stay>4 days in the last three months ("hospital"); antibiotherapy during one week in the last month ("antibiotic"); institutionalized patients or recurrent contact with healthcare ("institution or care"); MRM carrier in the last 6 months ("previous MRM"). Demographic data, culture results and isolation time. A multivariate analysis was performed using multiple logistic regression between each of the risk factors and patient MRM carrier status. During the study period, 575 patients were admitted, of which 28% met the isolation criteria (162). Fifty-one (31%) were MRM carriers. Of the patients who did not meet the criteria, 29 (7%) were carriers. In the multivariate analysis, the only variable independently associated to carrier status was "previous MRM", with OR=12.14 (95%CI 4.24-34.77). The only criterion independently associated with the ability to detect patients with MRMs upon admission to the ICU was the existence of "previous MRM".