Abstract
Objective To investigate the influence factors of central venous catheter related infections (CVC-RI)in postoperative patients with gastric carcinoma treated with parenteral nutrition, in order to provide scientific basis for prevention and treatment. Methods Using the retrospective study method, 150 patients who treated with parenteral nutrition after operation of gastric carcinoma from December 2013 to March 2014 were selected. Information including age, sex, anamnesis, catheter indwelling time, infusion rate of nutrient solution, and so on were collected. Patients with central venous catheter related infections were set as infection group, patients without infection as the control group, and the group logistic regression analysis was used to analyze the collected data. Results 21 patients in infection group had CVC-RI, and the incidence was 14.00% (21/150), while 129 patients in control group had CVC-RI. Univariate analysis showed there was significant difference between infection group and control group in age, anamnesis, catheter indwelling time and infusion rate of nutrient solution(χ2=17.126, 5.447, 12.795, 7.973,P 0.05); the group logistic regression analysis showed that age (OR=15.927, 95%CI 3.305-76.756,P<0.05) and catheter indwelling time (OR=3.511, 95%CI 1.028-11.992, P<0.05)were independent risk factors for CVC-RI, however infusion rate of nutrient solution (OR=0.140, 95%CI 0.033-0.597,P<0.05)was a protective factor. Conclusions For the postoperative patients with gastric carcinoma treated with parenteral nutrition, CVC-RI is closely related to age, catheter indwelling time and infusion rate of nutrient solution. So reducing catheter indwelling time, restoring the enteral nutrition under condition permission as so on as possible can reduce infection of elderly patients. Key words: Stomach neoplasms; Parenteral nutrition; Catheterization, central venous; Infection; Risk factors
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