Abstract
The incidence of liver cancer in China accounts for more than half of the world, and the majority of them is caused by hepatitis B and hepatitis C. China is known as a great contributor to hepatitis. The Chinese government has implemented a series of preventive measures to solve this problem, especially the policy of free hepatitis B vaccination for newborn babies and effectively reduced the incidence of hepatitis. The incidence of infectious diseases is often related to socio-economic factors. Therefore, we used data on the incidence of hepatitis B and C and socioeconomic factors to analyze and find out the relationship among them in various regions. There were high incidence areas and low incidence areas in China, and the high incidence area of hepatitis B was also the high incidence area of hepatitis C. Especially in Xinjiang, the highest incidence of hepatitis B and hepatitis C was observed at the same time. The incidence of hepatitis B and hepatitis C was more affected by regional economic factors. The economic factors in low incidence areas of hepatitis were better than those in high incidence areas. There was a negative correlation between economic factors and the incidence of hepatitis. In conclusion, in economically developed areas, the government has invested more money and resources in public health and people’s health awareness in comparison to underdeveloped areas. In the future, various preventive strategies should be carried out according to the background of different regions.
Highlights
Hepatitis B and C are the liver disease caused by the hepatitis B virus (HBV) and hepatitis C virus (HCV), respectively
Hepatitis B and hepatitis C are responsible for 96% of all hepatitis-related mortality to the hepatocellular carcinoma (HCC)-related virus; HBV is accountable for 70% - 80%, while HCV is for 10% - 20% of virus-associated HCC [3]
The areas which incidence higher than median incidence were set as high incidence area, and the area’s incidence lower than the median incidence rate were set as low incidence area
Summary
Hepatitis B and C are the liver disease caused by the hepatitis B virus (HBV) and hepatitis C virus (HCV), respectively. The World Health Organization (WHO) estimated that globally 257 million and 71 million people are living with HBV and HCV infection and accounted for 887,000 deaths in 2015 and 399,000 deaths every year, respectively [1]. The death is mostly due to complications as cirrhosis and hepatocellular carcinoma (HCC) [2]. Hepatitis B and hepatitis C are responsible for 96% of all hepatitis-related mortality to the HCC-related virus; HBV is accountable for 70% - 80%, while HCV is for 10% - 20% of virus-associated HCC [3]. HBV & HCV coinfection with other blood-borne viruses is associated with a higher likelihood of progressions to cirrhosis, HCC and related mortality [4]
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