Abstract
Analysis of the IgE epitope profile of soybean allergen Gly m 4
Highlights
Individuals with birch pollinosis may show allergic reactions after consumption of soybean-containing food
Specific IgE against Bet v 1 and Gly m 4 was determined by ImmunoCAP
IgE binding of the sera to rGly m 4 and soy extract was tested in western blot analysis
Summary
Individuals with birch pollinosis may show allergic reactions after consumption of soybean-containing food. This is caused by cross-reaction of IgE directed against the major birch pollen allergen Bet v 1 with its homologue Gly m 4 from soybean. Birch pollen allergic subjects without soybean allergy often present IgE binding to Gly m 4
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