Abstract

Eighty patients with prostatic carcinoma were treated by antiandrogen therapy with chlormadinone acetate and diethylstilbestrol diphosphate. Numerous papers have shown that the survival rates of patients with low-grade prostatic carcinomas are higher than those of patients in advanced stages; however, in this study, no statistically significant difference in the ten-year survival rates of these groups was demonstrated. Residual cancer cells in the primary lesions were observed in 90% of the patients who underwent autopsy following death. The results of this study suggest that antiandrogen therapy is not sufficiently effective for the treatment of patients with prostatic carcinoma.

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