Abstract

Deaths attributable to preventable medical errors (PME) in hospitals exceed those caused by well-known life-threatening conditions, such as motor vehicle accidents, breast cancer, and AIDS [1]. The Institute of Medicine estimates that as many as 98,000 deaths are caused by PME every year [1]. The risks derived from PME are even more severe when they affect critically ill patients, or include medications that must be adjusted for the patient's body weight. Fatigue and work overload can represent a threaten to the patients' safety in pediatric ICUs [2]. Expert Systems (ES) [3], a branch of artificial intelligence, can be used to solve the problems related to medical prescription errors (MPE). Studies analyzing the role of ES in MPE are still lacking. The objective of this study was to compare the accuracy of an experimental ES with the written medical prescription.

Highlights

  • Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition

  • The objective of this study was to verify the incidence of delirium through the CAM ICU instrument in ICU patients followed by physiotherapists

  • There was a low incidence of delirium in ICU patients followed by physiotherapists

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Summary

Introduction

Vascular calcification is a regulated process, which associates with coronary artery disease (CAD) and occurs through an increase in transcription factor expression such as RUNX2, MSX2 and alkaline phosphatase (ALP), inducing calcium deposition. The objective of this study was to evaluate the tendency of the plasma concentration and clearance of PCT as biomarkers for prognosis of patients with severe sepsis and septic shock, compared with another early prognosis marker, the number of SIRS criteria at sepsis diagnosis. The objective of this study was to evaluate the serum activity of MMP-2 and MMP-9, length of hospital stay, length of ICU stay and mortality in patients with septic shock. The objective of this study was to determine the influence of serum thiamine concentrations on lactate levels, GPx activity, length of hospital stay, length of ICU stay and ICU mortality in patients with septic shock. Hypothermia at ICU admission was associated with greater severity scores and increased hospital mortality in this sample of surgical patients studied.

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