Abstract
Objective To investigate the effect of intensive management and achieving the target control more than 3 times on endpoint events during 9 consecutive years' annual assessment in type 2 diabetes (T2DM) patients in the Sanlitun Community Health Service Center in Beijing, including blood glucose, blood pressure, lipids profiles, and the joint target control. Methods In Beijing Community Diabetes Study (BCDS), 224 patients with T2DM from the Sanlitun Community Health Service Center were enrolled in 2008. All patients were randomly assigned to the intensive management group (n = 113) and the standard management group (n = 113) and the standard management group (Results During the nine-year follow-up, the abscission number was 35 (14.29%), among which 14 (12.39%) was in the intensive management group and 21 (18.92%) was in the standard management group. The incidence of diabetic retinopathy (6 cases, 5.41%) and diabetic nephropathy (13 cases, 11.71%) in the standard management group was significantly higher than that in the intensive management group (1 case, 0.88%; 5 cases, 4.42%), respectively (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (P < 0.05). However, there were no significant differences on the other endpoint events between the two groups (Conclusions The intensive management can effectively reduce the occurrence of microvascular complications. The incidence of all-cause death and the other endpoint events decreased in T2DM patients who achieved the joint target control more than 3 times during the nine-year management, which improved survival time and life quality. This trial is registered with ChiCTR-TRC-13003978 and ChiCTR-OOC-15006090.
Highlights
Type 2 diabetes (T2DM) is a complex chronic disease, which requires continuous medical intervention
A large number of evidence-based studies have confirmed that the joint target control of blood glucose, blood pressure, blood lipid, and other risk factors is the key to the prevention and treatment of chronic complications of diabetes [3], there are few reports on the effect of intensive management and number of times achieving the target control on endpoint events in T2DM. e Beijing Community Diabetes Study (BCDS) project, which began in 2008, went deep into the districts and counties of Beijing, trained community health care personnel, and improved the comprehensive ability of community health care units for diabetes management
There were no significant differences in age, sex, body mass index (BMI), duration of diabetes, and urinary albumin excretion rate (UAER) between two groups (Table 1)
Summary
Type 2 diabetes (T2DM) is a complex chronic disease, which requires continuous medical intervention. A large number of evidence-based studies have confirmed that the joint target control of blood glucose, blood pressure, blood lipid, and other risk factors is the key to the prevention and treatment of chronic complications of diabetes [3], there are few reports on the effect of intensive management and number of times achieving the target control on endpoint events in T2DM. From the beginning of the project, 224 patients with T2DM in Sanlitun Community Health Service Center were followed up for 9 years, monitored regularly, and standardized the diabetes management process. E purpose of this study was to analyze all-cause endpoints events that occurred during 9 consecutive years of follow-up and to explore the benefit of quality of life of patients with T2DM in urban community after management From the beginning of the project, 224 patients with T2DM in Sanlitun Community Health Service Center were followed up for 9 years, monitored regularly, and standardized the diabetes management process. e purpose of this study was to analyze all-cause endpoints events that occurred during 9 consecutive years of follow-up and to explore the benefit of quality of life of patients with T2DM in urban community after management
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