Abstract
Introduction: Over time, treatments with plant species have become more effective for the vast majority of the population, even with a vague collection of scientific research that proves their safety and effectiveness. Among these different species is the arboreal Crescentia cujete L., which is widely distributed in Northeastern Brazil. It is applied with various therapeutic purposes, from antihypertensive, analgesic, antispasmodic and some gynecological disorders. Objective: To analyze the possible cytotoxicity of the hydroalcoholic extract of the fruit. Methodology: The extract was obtained through dynamic maceration in a hydroalcoholic solution. A cytotoxicity analysis was carried out based on the methodologies of osmotic fragility and lethality against Artemia salina L. 45.32%. Conclusion: Therefore, further research aimed at safety and possible applicability of the extract in question is encouraged.
Highlights
Over time, treatments with plant species have become more effective for the vast majority of the population, even with a vague collection of scientific research that proves their safety and effectiveness
Brazil has one of the greatest biodiversity on the planet, accounting for around 55,000 species of plants, many of which are restricted to a certain area and in some cases popular knowledge has low levels or is even nil
There are data that indicate that only 5% of these plants have been studied for their chemical compounds and a smaller percentage is seen when considering the evaluation of their biological aspects (Paulo, 2016). Faced with this vast biodiversity is the Crescentia cujete L., belonging to the Bignoniaceae family, these are characterized as shrubs, vines and arboreal, are configured as a small tree and can hold flowers with yellowish green color and fruits with a spherical shape (Araújo, 2015)
Summary
Treatments with plant species have become more effective for the vast majority of the population, even with a vague collection of scientific research that proves their safety and effectiveness Among these different species is the arboreal Crescentia cujete L., which is widely distributed in Northeastern Brazil. There are data that indicate that only 5% of these plants have been studied for their chemical compounds and a smaller percentage is seen when considering the evaluation of their biological aspects (Paulo, 2016) Faced with this vast biodiversity is the Crescentia cujete L., belonging to the Bignoniaceae family, these are characterized as shrubs, vines and arboreal, are configured as a small tree and can hold flowers with yellowish green color and fruits with a spherical shape (Araújo, 2015). They hold several chemical components, including flavonoids, terpenoids and quinones, but mainly naphthoquinones and aromatic compounds (Lima, et al, 2020)
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