Analysis of the controlled essential hypertension’s pharmacotherapy in general practice

Abstract

BACKGROUND: Arterial hypertension is a common cardiovascular disease that requires constant monitoring by a doctor of drug therapy to achieve the target blood pressure level.
 AIM: To analyze pharmacotherapy of essential hypertension in patients, who have achieved a controlled course of the disease.
 MATERIALS AND METHODS: In this study 274 patients with controlled course of stage 2 arterial hypertension and no comorbidities were recruited. Blood pressure indicators, anthropometric data, results of laboratory and instrumental studies, the volume of drug therapy for hypertension were analyzed.
 RESULTS: We analyzed 543 drug prescriptions for 274 patients with stage II hypertension. In 97 (35.3%) patients only one drug was prescribed, in 112 (40.7%) two drugs, in 46 (16.7%) three drugs from various pharmacological groups, among which monodrugs were in the lead: angiotensin-converting-enzyme inhibitors 31.86%, cardioselective -blockers 23%, angiotensin 2 receptor blockers 9.3%. Combined drugs were present in 18.4% of general doctors prescriptions. Fixed forms of combined antihypertensive drugs were taken by only 50 (18.4%) patients. To prevent cardiovascular complications of arterial hypertension, 75 (26%) patients were prescribed statins (atorvastatin or rosuvastatin) and 56 (19.5%) antiplatelet monotherapy with Cardiomagnyl, Thrombo ACC or clopidogrel.
 CONCLUSIONS: To achieve the target blood pressure level and control arterial hypertension in patients with stage II hypertension, general practitioners used all main