Abstract
Aim: This study aimed to examine the consistency of quality of life and depression scales using information obtained from
 individuals with Alzheimer disease (AD) and the family members of these patients.
 Material and Methods: Mini-Mental State Examination (MMSE) score was ≥14 points patients who were diagnosed with
 AD (n:86) and their families(n:86) participated in the study. All individuals took the Geriatric Depression Scale Short Form
 (GDS-SF), Nottingham Health Profile (NHP) and World Health Organization Quality of Life Instrument Elderly Module
 Turkish Version (WHOQOL-OLD). Data obtained from 78 patients and their relatives who have completed all of the
 questions in the scales were evaluated. Patient and family scale scores were compared using correlation analysis and
 difference analysis.
 Results: A moderate to very high correlation was found between the GDS-SF, NHP, and WHOQOL results of the patients
 and their relatives (0.447-0.848). It was detected that while NHP correlation coefficients varied between 0.734 and 0.848,
 WHOQOL-OLD correlation coefficients varied between 0.447 and 0.696. When the difference between the scores of the
 answers given by the patient and his family was examined, a statistically significant difference was found only in the mean
 scores of NHP sleep, WHOQOL sensory ability, WHOQOL social participation and WHOQOL raw (p < 0.05).
 Conclusion: In conclusion, NHP, GDS-SF, and WHOQOL-OLD consistency between the individual with AD diagnosis and
 their family. However, if information is to be obtained from the patient in evaluating the quality of life, choosing NHP
 instead of WHOQOL-OLD may lead to more accurate results.
Highlights
Alzheimer’s disease (AD), characterized by cognitive loss, is a progressive neurodegenerative disease that causes various behavioral problems and impairment in quality of life of the patients
Among the patients who were admitted to the dementia polyclinic between the months of May 2019 and September 2019; individuals who were diagnosed with AD according to DSM 5 criteria, whose Mini-Mental State Examination (MMSE) score was ≥14 points, who and/or whose family volunteered to participate were included in the study
While there was an inconsistency in 1 subsection in Nottingham Health Profile (NHP), the presence of inconsistencies in 2 subdomains and raw scores in WHOQOL-OLD and lower correlation coefficients compared to NHP suggested that NHP could give more accurate results than WHOQOL in evaluating the quality of life
Summary
Alzheimer’s disease (AD), characterized by cognitive loss, is a progressive neurodegenerative disease that causes various behavioral problems and impairment in quality of life of the patients. There are discussions in literature on the definition of the quality of life of patients with dementia, its measurability, and from whom should the information be gathered while evaluating the quality of life [4,5,6]. Causes such as cognitive impairment, cognitive impairment, immediate memory impairment, verbal communication deficiencies, and loss of insight among dementia patients make it difficult for the individual to assess his/her own quality of life [7]. In studies regarding the analysis of the quality of life of individuals with AD, it is stated that patients with mild to moderate cognitive impairment are able to give opinions regarding their subjective states [3, 8, 9]
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