Analysis of the complication incidence in performing ultrasound-guided percutaneous biopsy of peripheral pulmonary neoplasm

Abstract

Objective To explore the influence factors and incidence of complications in ultrasound-guided biopsy of peripheral pulmonary neoplasm, in order to decrease the incidence of complications and improve the safety. Methods The age of 168 cases (male: 93, female: 75) was 29~87 years old (average age was 60.8±10.7). The data of ultrasound-guided percutaneous lung biopsy in the first hospital affiliated to Xi′an Jiaotong University from January 2013 to December 2017 were retrospectively analyzed.The incidence of complications such as pneumothorax, hemoptysis and pleural reaction was statistically analyzed.To study the relationship of complications with age, gender, puncture times, puncture depth, neoplasm size, blood supply status and presence of necrosis. Results The incidence of complications was 11.31%(19/168), including pneumothorax 5.95%(10/168), hemoptysis 4.17%(7/168), pleural reaction 1.19%(2/168). There was no tumor cell metastasis, chest infection, hemothorax, embolism, cardiac respiratory arrest.In univariate Logistic regression analysis, there were significant differences in the incidence of complications with different puncture times, puncture depth and neoplasm size (all P 0.05). In multivariate Logistic regression analysis, the diameter of the neoplasm was a protective factor for the incidence of complications (β=-1.225, OR=0.294), while puncture times (β=1.238, OR=3.449) and puncture depth (β=1.548, OR=4.702) were risk factors for the incidence of complications. Conclusions The ultrasound-guided biopsy of peripheral pulmonary neoplasm was safe and efficient.The times and depth of thoracic puncture, neoplasm size were the independent factors for the incidence of complications. Key words: Ultrasonography; Biopsy, needle; Postoperative complications; Pulmonary neoplasm