Analysis of the compliance and affective factors about antiplatelet therapy in patients with coronary heart disease one year after hospitalization

Abstract

Objective To analyze the compliance of antiplatelet therapy and its affective factors in patients with coronary heart disease one year after hospitalization, which will improve the secondary prevention for coronary heart disease. Methods The study enrolled 398 patients (363 patients completed the study) with first-diagnosed coronary heart disease in a provincial hospital in Anhui province from January to December 2012. The therapeutic compliance of these patients, as well as the affective factors, were evaluated with a self-designed questionnaire either through phone revisit or out-patient interview. The factors influencing therapeutic compliance of patients with coronary heart disease were analyzed by Logistic regression analysis. Results The results showed 301 (83%) patients were in a good therapeutic compliance, while the rest of 62 (17%) patients were not. The affective factors included age, ways of medical payment, whether with PCI treatment or not, and the types of coronary heart disease (stable angina, unstable angina and acute myocardial infarction), χ2 values were 9.425, 6.262, 5.556 and 6.895. The main affective factors were the age [OR=0.471(0.284-0.782)] and whether with PCI therapy or not [OR=2.104(1.123-3.942)]. Conclusions Patients had poor compliance of antiplatelet therapy one year after hospitalization, medical staffs should make treatment protocol and nursing measures according to age and whether with PCI treatment or not of patients, so that the belief and behavior of medication can be intensified, the medication compliance can be elevated and the secondary prevention can be well implemented. Key words: Coronary artery disease; Platelet aggregation inhibitors; Medication adherence