Abstract
Objective Analysis the clinical features of chronic obstructive pulmonary disease (COPD) with chronic pulmonary embolism,to strengthen the understanding of the in situ pulmonary embolism in patients with COPD,to provide the clinical experience of diagnosis and treatment of COPD combined with chronic pulmonary embolism for basic-level hospitals.Methods We selected 53 COPD complicated with PE patients defined as research group,while selected 70 COPD patients in the same period defined as control group,compare the differences of clinical characteristics between the two groups.Observe the curative effect of the case group after anticoagulant therapy.Results There were no difference in D-dimmer and double lower limbs vein ultrasound between the two groups,but Hemoglobin levels,6 minutes walk test,CAT scores,mMRC score,PaCO2,PaO2,A-aDO2,FEV1 ％ pred,pulmonary artery systolic pressure have obvious differences (P ＜0.05).After anticoagulation,the above indexes were obviously improved.Conclusions Chronic pulmonary embolism is an important factor which causes stubborn hypoxemia and poor activity of COPD.Anticoagulant therapy has reliable clinical value for COPD combine with chronic pulmonary embolism. Key words: Chronic obstructive pulmonary disease; Pulmonary embolism; Chronic; Hypoxemia; Anticoagulant therapy
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