Abstract

Ovarian cancer is the most aggressive form of all malignant neoplasms of the female reproductive system. Despite certain advances achieved in the diagnosis and treatment of this disease, survival rates are still unsatisfactory, which dictates the need for further study of the etiological factors and pathogenetic mechanisms underlying ovarian carcinogenesis. The purpose of the work was to conduct an association analysis of the rs3218536 polymorphic variant of the XRCC2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortostan. As a result of the study, it was not possible to detect an association of the studied polymorphic locus with the risk of developing ovarian cancer in women from the Republic of Bashkortostan

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