Analysis of the Allele Polymorphism of (CTG) n and (CAG) n Triplet Repeats in Loci DM, DRPLA, and SCA1 in Several Populations of Russia

S N Popova,S A Limborska,V A Spitsyn,P A Slominsky,L A Tarskaya,I A Guseva,S N Galushkin

doi:10.1023/a:1021159413816

Analysis of the Allele Polymorphism of (CTG) n and (CAG) n Triplet Repeats in Loci DM, DRPLA, and SCA1 in Several Populations of Russia

S N Popova, S A Limborska + Show 5 more

https://doi.org/10.1023/a:1021159413816

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Journal: Russian Journal of Genetics	Publication Date: Jan 1, 2002
Citations: 8

Affiliation: Institute of Molecular Genetics, Lomonosov Moscow State University

#Spinocerebellar Ataxia Type 1 #Dentatorubral-pallidoluysian Atrophy + Show 8 more

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Abstract

Polymorphism of highly polymorphic triplet repeats CTG of the 3"-untranslated region of the myotonin protein kinase gene and CAG of the genes associated with dentatorubral-pallidoluysian atrophy (DRPLA, or Hew River syndrome) and spinocerebellar ataxia type 1 (SCA1) was analyzed in several ethnic populations of Russia. A difference in allele spectra of the three genes was demonstrated for populations differing in ethnic origin.

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