Analysis of surgicaltreatment for congenital blepharophimosis syndrome

Abstract

：Objective To investigatethe outcome of the surgical treatment for congenital blepharophimosis syndrome. MethodsThis was a retrospective case study to analyze a treatment approach for congenitalblepharophimosis syndrome and its clinical efficacy. A bilateral correction of theepicanthus and blepharoptosis was performed simultaneously. Suitable methods were adoptedto correct the epicanthus: Y-V, Stallars Z , Speath and classic Mastands.Twenty-three patients (46 eyes) were involved in the study, ranging in age from 2 to 11years. All patients suffered from eye or systemic disease. There were cases of strabismus,refractive error, amblyopia, inherited and systemic disease. The study analyzedeffectiveness by comparing the preoperative and postoperative status of palpebral fissurelength, palpebral fissure width, inner canthic diameter and eyebrow-eyelid diameter usinga paired t-test. Patients were followed up for 1 to 24 months after the operation. ResultsThere was an obvious improvement in palpebral fissure length and palpebral fissure widthin all patients, and an obvious decrease in the inner canthic diameter and eyebrow-eyeliddiameter. Comparisons one month after the operation showed that palpebral fissure lengthchanged from (18.5±1.1)mm to (23.4±1.2)mm, palpebral fissure width changed from (2.1±1.2)mmto (6.7±0.9)mm, inner canthic diameter changed from (35.2±1.4)mm to (31.1±1.1)mm, andeyebrow-eyelid diameter changed from (13.6±1.3)mm to (9.8±1.2)mm. The differences werestatistically significant (P<0.05). There was only one case with complication ofexposure keratitis after the operation. Conclusion For congenital blepharophimosissyndrome with refractive errors and amblyopia, it is better to perform a bilateralcorrection of the epicanthus and blepharoptosis simultaneously, which is a more idealapproach than other treatments.