Analysis of surgical approach and tumor distance to margin after liver resection for colorectal liver metastasis.

Abstract

This study was undertaken to compare tumor distance to margin after robotic vs. open hepatectomy for colorectal liver metastases (CLM) and to determine the relationship between perioperative variables, surgical approach and tumor distance to margin with overall survival. With IRB approval, we followed 56 patients who underwent a robotic or open hepatectomy for treatment of CLM. The relationships between the tumor distance to margin, operative approach, perioperative variables and survival was determined. The robotic approach yielded greater margins than the open approach (p = 0.04). The robotic vs. open approach had an operative duration of 375 vs. 269min (p = 0.05), ICU length of stay (LOS) of 0 vs. 1day (p = 0.01), and hospital LOS of 4 vs. 7days (p = 0.04). Patients with a tumor distance to margin of ≤ 1mm and 1.1-9.9mm had an estimated median survival of 49months and 24months, respectively. Estimated median survival for patients with tumor distance to margin of ≥ 10mm has not been reached but is > 84months. The use of the robotic approach is associated with greater tumor distance to margin and shorter hospital LOS, but with longer operations. The robotic approach does not compromise oncological margins during resection for CLM.