Abstract

Background: Heavy metals, which are likely to be found in natural water samples, can cause some discomfort when taken into the body in high amounts. The aim of this study is to create complexes of iron, copper and cadmium, which are major heavy metals that can be found in natural water samples, with ammonium pyrrolidine dithiocarbamate (APDC) chelate, to analyze these complexes with UV-Spectrophotometry after the optimum conditions to be created in water samples, and to apply the principal component regression chemometric method to the data obtained here. Method: In the applied spectrophotometric method, complexes of each heavy metal were first formed with APDC. Then, appropriate mixtures of these complexes were prepared and their spectra were recorded. Principal component regression chemometric method was applied to the data obtained. Results: Very consistent results of the chemometric method applied to the data obtained in the spectrophotometric analysis of the complexes of the heavy metals studied after providing optimum conditions were observed. Conclusion: It can be stated that the method developed in the research and the chemometric method applied to the data obtained from here can be easily applied in routine water analysis.                        Peer Review History: Received 10 December 2023;   Revised 29  January 2024; Accepted 3 March; Available online 15 March 2024 Academic Editor: Dr. Emmanuel O. Olorunsola, Department of Pharmaceutics & Pharmaceutical Technology, University of Uyo, Nigeria, olorunsolaeo@yahoo.com Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Dr. Dennis Amaechi, MrsFoluBabade Mini Estate , Flat 5 by Old Soldiers Quarter, Sabongari/Bwari, Abuja- Federal Capital Territory, Nigeria. amaechitoexcel@yahoo.com  Dr. Wafa Mohamed Al Madhagi, Sana’a University, Yemen, walmadhaji1983@gmail.com Prof. Cyprian Ogbonna ONYEJI, Obafemi Awolowo University, Ile-Ife, Nigeria, conyeji@oauife.edu.ng

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