Year-end Sale % OFF 
Abstract
Patients diagnosed with Parkinson’s disease present sleep disorders with a higher frequency than the general population. The sleep architecture in these patients shows variations with respect to the normal population, so in this work it was decided to investigate the characteristics of the macroarchitecture of sleep in patients diagnosed with Parkinson’s disease. A polysomnographic study was carried out on 77 patients diagnosed with Parkinson’s disease. All the studies were processed according to the AASM Manual for the Scoring of Sleep and Associated Events v.2.2, and to the criteria of the International Classification of Sleep Disorders 3rd ed. (2014). Processing was carried out using descriptive statistics, as well as non-parametric analysis for comparison between cases and controls. The group of patients showed significant reductions of the N2, N3, and REM sleep stages when compared with a control group, as well as a significant increase in intra-sleep wakefulness. The number of REM–NoREM sleep cycles and sleep efficiency showed marked reduction compared to the control group. There was a statistically significant difference in the macroarchitecture of sleep between patients diagnosed with Parkinson’s disease and healthy controls.
Highlights
During normal adult sleep there is an orderly progression from wakefulness to the onset of sleep, and once in the sleep period, the normal transition occurs from the no rapid eye movement (NREM)
A polysomnographic study (PSG) was carried out on 77 patients diagnosed with Parkinson’s polysomnographic study (PSG) was carried out on 77 patients diagnosed with Parkinson’s disease,Awith an average age of 57.47 years. 64 patients (77.9%) were male, and 58% of patients were in disease, with an average age of 57.47 years. 64 patients (77.9%) were male, and 58% of patients were stage II of Hoehn and Yard and 41% of patients in stage III respectively (Table 1)
The present study is based on the hypothesis that the sleep disorders observed in patients with Parkinson’s disease (PD) are very frequent and varied in their manifestations, but that these can affect the macroarchitecture of sleep in these patients in different ways
Summary
During normal adult sleep there is an orderly progression from wakefulness to the onset of sleep, and once in the sleep period, the normal transition occurs from the no rapid eye movement (NREM). Sleep, to rapid eye movement (REM) sleep. NREM sleep is characterized by a progressive decrease in the response to external stimuli, accompanied by slow eye movements, followed by a slow wave activity on the electroencephalogram (EEG) associated both with the appearance of sleep spindles and. REM sleep is distinguished by the presence of rapid eye movements, further reduction of the response to stimuli, absence of muscle tone, and rapid activity and low voltage in the EEG, combined with the presence of waves with a distinctive sawtooth configuration.
Sign-in/Register to view highlights & summary 
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
