[Analysis of serum inhaled allergens in children with adenoid hypertrophy in Yantai area].

Abstract

Objective:The results of the detection of the serum inhalant allergen in children with adenoid hypertrophy in Yantai were analyzed, and the common inhalant allergens and their distribution in the children with adenoid hypertrophy were found. Method:Serum inhaled allergen specific IgE（sIgE） was measured in 590 cases of adenoid hypertrophy from Nov 2017 to Oct 2018 by Symer allergen detection system, and stratified according to sex, age and visiting season. The distribution of inhaled allergens in serum of children with adenoid hypertrophy was described. Result:The positive rate of serum inhaled allergens in children with adenoid hypertrophy in Yantai area was 34.07%. Among them the most common inhaled allergens were dust mite（19.66%）, dust mite（18.98%） and the mixed mold（17.97%）. The positive degree of allergen in children with adenoid hypertrophy was mild（93 cases）, moderate（88 cases）, and severe（20 cases）. 76 cases were positive for single allergens, 79 cases were positive for 2 allergens, and 56 cases were positive for three or more allergens. Stratified study showed that there was no significant difference in the positive rate of inhaled allergens between male and female children（P>0.05）, but the positive rate of mixed mold and animal dandruff allergens in male children was higher than that in female children（P<0.05）. There was no significant difference in the positive rate of inhaled allergens between pre-school and school-age children（P>0.05）, and there was no significant difference in the positive rate of inhaled allergens in different seasons（P>0.05）. Conclusion:Dust mite, dust mite and mildew mixture were the most common inhaled allergens in children with adenoid hypertrophy in Yantai area. The positive degree of serum allergens in children with adenoid hypertrophy was mild to moderate, and most of the children were allergic to two kinds of allergens. Male children were more susceptible to mold mixing and animal dandruff. There was no significant difference in age and seasonal distribution of common inhaled allergens.