Analysis of risk factors of neurological deterioration in patients with ischemic stroke

Abstract

Objective To analyze the risk factors of early neurological deterioration in patients with ischemic stroke, and to investigate the relationship between different types of stroke and early neurological function. Methods Four hundred and twenty patients with ischemic cerebral infarction were selected. The patients were divided into END group with 108 cases and stable group with 312 cases. OCSP lesion type and TOAST pathological type were divided, related factors of hypertension, diabetes mellitus, records of pathological lesions typing were recored. After 2 months of follow-up, using the modified Rankin scale and Barthel Index to evaluate the prognosis of patients. Results The onset time of END group was significantly shorter than that in the stable group, the fasting blood glucose level was significantly higher than that of the stable group, the difference was significant(P 0.05). The prognosis of patients in group END was significantly worse than that in stable group, the difference was significant(P<0.01). Admission from onset time shorter and elevated fasting blood glucose were the risk factors of END; LACI type less disturbance of consciousness, elevated fasting blood glucose were more prone to disturbance of consciousness and movement disorders, PACI was more prone to language barriers. Conclusions Hyperglycemia in patients with ischemic stroke is the main factor to predict the deterioration of early neurological function. OCSP and TOAST typing are helpful to identify high-risk patients. Key words: Ischemic stroke; Early neurological deterioration; Risk factor