Abstract
ABSTRACTPurpose:To determine risk factors of postoperative urethral stricture (US) and vesical neck contracture (BNC) after transurethral resection of prostate (TURP) from perioperative parameters.Materials and Methods:373 patients underwent TURP in a Chinese center for lower urinary tract symptoms suggestive of benign prostatic obstruction (LUTS/BPO), with their perioperative and follow-up clinical data being collected. Univariate analyses were used to determine variables which had correlation with the incidence of US and BNC before logistic regression being applied to find out independent risk factors.Results:The median follow-up was 29.3 months with the incidence of US and BNC being 7.8% and 5.4% respectively. Resection speed, reduction in hemoglobin (ΔHb) and hematocrit (ΔHCT) levels, incidence of urethral mucosa rupture, re-catheterization and continuous infection had significant correlation with US, while PSA level, storage score, total prostate volume (TPV), transitional zone volume (TZV), transitional zone index (TZI), resection time and resected gland weight had significant correlation with BNC. Lower resection speed (OR=0.48), urethral mucosa rupture (OR=2.44) and continuous infection (OR=1.49) as well as higher storage score (OR=2.51) and lower TPV (OR=0.15) were found to be the independent risk factors of US and BNC respectively.Conclusions:Lower resection speed, intraoperative urethral mucosa rupture and postoperative continuous infection were associated with a higher risk of US while severer storage phase symptom and smaller prostate size were associated with a higher risk of BNC after TURP.
Highlights
Been widely used since the 1970s, transurethral resection of prostate (TURP) has been the most popular treatment of lower urinary tract symptoms suggestive of benign prostatic obstruction (LUTS/BPO)
We aimed to investigate the influence of specific perioperative clinical parameters on the occurrences of urethral stricture (US) and bladder neck contracture (BNC) after TURP, further disclosing available risk factors and assessing their force of inducing US and BNC
After being inquired with a detailed clinical history, LUTS/BPO related subjective symptom were measured by the International Prostate Symptoms Score (IPSS) system consisting of storage and voiding phase score and the quality-of-life (QoL) questionnaires
Summary
Been widely used since the 1970s, transurethral resection of prostate (TURP) has been the most popular treatment of lower urinary tract symptoms suggestive of benign prostatic obstruction (LUTS/BPO). TURP is still the major surgical method in developing countries ibju | Risk factors leading to postoperative urethral stricture and bladder neck contracture following TURP including China for its lower cost and favorable outcome. Postoperative dysuria is often caused by urethral stricture (US) and bladder neck contracture (BNC), the incidences of which were reported from 0.3 to 9.2% and 2.2 to 9.8% respectively, in contemporary literature [8,9,10]. Many factors have been verified to correlate with high risks of US or BNC including unmanaged preoperative infection, unsuitable diameters of resectoscope, long resection duration time and postoperative catheterization, etc. We aimed to investigate the influence of specific perioperative clinical parameters on the occurrences of US and BNC after TURP, further disclosing available risk factors and assessing their force of inducing US and BNC
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
